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Abstract: A fabrication system for artificial bioactive bone
manufacturing is set up. The artificial bone constructed in this system
has the exact external form of the replaced bone and a 3D scaffold
simulating the microvaso system of bone tissue in the interior. Through
attaching the skeletal growth factor and viable cells to the 3D
scaffold, the artificial bone can attain bioactivity. This approach can
improve the traditional method that cannot realize osteoinduction
because the filling biomaterial has not activity. The animal experiment
results show that the interior simulation structures of the Volkmann's
canal and Haversian canal can provide proper space for the 3D growth of
the osteocyte and quick activation of the artificial bone, and hence can
effectively speed up the quick activation of the artificial bone.
Key words: Rapid prototyping Artificial bone Bioactive
CLC No: TH12
TB17
国家自然科学基金资助项目(50235020).
Received 20021119, received in revised form 20030430
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