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Abstract: A plastic capillary electrophoresis chip is a novel kind of
miniaturized device for biochemistry analysis. The major advantages of
the chip include high transmittance for light; low conductivity for
electrokinetic pumping and electrophoretic separation; low cost for
high volume production and disposal and easily manufacturing for high
aspect ratio of microchannels on the chip. A process of thermal bonding
for plastic capillary electrophoresis chips is studied, the
relationships between the changes of the dimensions of the microchannels
and the process conditions of thermal bonding and hot embossing,
including temperature, pressure and time are established by experiment,
based on these the ways to reduce the changes are proposed, which lays
the foundation for basic theories and techniques of structural design
and manufactures of the plastic chip.
Key words: Capillary electrophoresis chips Microfluidic chips Biochips
m-TAS MEMS Microfabrication Thermal bonding
CLC No: TN271
中国博士后科学基金和吉林省科技发展计划资助项目(20020610).
Received 20040413, received in revised form 20041026
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