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  HomeContents of Chinese Journal of Mechanical Engineering (English Edition),2007 No.5NUMERICAL SIMULATION BY COMPUTATIONAL FLUID DYNAMICS AND EXPERIMENTAL STUDY ON STIRRED BIOREACTOR WITH PUNCHED IMPELLER

WANG Yu
College of Food Science and Technology,
Nanjing Agricultural University,
Nanjing 210095, China

HE Pingting
College of Material Science and Technology,
Nanjing University of Aeronautics
and Astronautics
Nanjing 210016, China

YE Hong

XIN Zhihong
College of Food Science and Technology,
Nanjing Agricultural University,
Nanjing 210095, China

 

 

NUMERICAL SIMULATION BY
COMPUTATIONAL FLUID DYNAMICS
AND EXPERIMENTAL STUDY ON
STIRRED BIOREACTOR WITH
PUNCHED IMPELLER

 

Abstract: Instantaneous flow field and temperature field of the two-phase fluid are measured by particle image velocimetry (PIV) and steady state method during the state of onflow. A turbulent two-phase fluid model of stirred bioreactor with punched impeller is established by the computational fluid dynamics (CFD), using a rotating coordinate system and sliding mesh to describe the relative motion between impeller and baffles. The simulation and experiment results of flow and temperature field prove their warps are less than 10% and the mathematic model can well simulate the fields, which will also provide the study on optimized-design and scale-up of bioreactors with reference value.

Key words: Stirred bioreactor with punched impeller Computational fluid dynamics (CFD) Particle image velocimetry (PIV) Flow field Temperature field

 


* This project is supported by Provincial Science and Technology Committee of Jiangsu, China (No. BJ99025). Received October 17, 2006; received in revised form May 27, 2007; accepted July 2, 2007

 

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